Alsa operate 2 direct bus service daily from Madrid to Lisbon. A day bus departs Madrid Estacion Sur at 0930 and arrives at Lisbon Oriente at 1645. A night bus departs Madrid Intercam Av America at 2200 and arrives the next morning at 0615 at Lisbon Oriente.
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Click to go to Madrid Travel Guide | Click to go to Lisbon Travel Guide
